Will not run?

Hello,

If you are able to make the engine run with pouring fuel into the throttle, then the issue is fuel related.
You could have a bad fuel pump, fuel pump regulator or a bad relay.
First of all can you hear the fuel pump come on when you turn the key to the on position?
If you can hear the pump then check fuel pressure. Inadequate or no pressure will make the engine not to start.
A bad fuel pressure regulator can prevent fuel from reaching the engine. It can also be due to a clogged fuel line.
With the key on and engine off you should have 60-66 PSI of fuel pressure.

Here is a helpful article on how to test fuel pressure:

https://www.2carpros.com/articles/how-to-check-fuel-system-pressure-and-regulator

If you do not hear the pump come on when turning on the key then first check the fuel pump relay.
That relay is located behind the glovebox compartment on the passenger side (see diagram).
Inspect the relay for any corrosion or burnt pin(s).
The relay can also be tested:

https://www.2carpros.com/articles/how-to-check-an-electrical-relay-and-wiring-control-circuit

If the rely is bad replace it. If the relay is good then check to see if you have getting power to the fuel pump connector. If you have power to that connector then you have a bad fuel pump. If there is no power then you will have to check the wiring harness.

https://www.2carpros.com/articles/how-to-replace-an-electric-fuel-pump

I have attached the diagrams for your reference.

Please let me know of any questions.
Thank you.

Hello, I'm Danny.

It sounds like you might be having an issue with a weak or failed in-tank electric fuel pump. Here is a tutorial showing how to replace an in-tank fuel pump:

https://www.2carpros.com/articles/how-to-replace-an-electric-fuel-pump

I've attached picture steps below on how to replace the in-tank fuel pump on your S-10. There are two ways to gain access. you can either drop the fuel tank or remove the bed whichever you find easiest to do. I've also attached the fuel pressure specification below as well. If you don't have access to a fuel pressure tester most auto parts stores have a tool loaner program and can loan you one. Here is a tutorial showing how to test the fuel pressure after completing the repair:

https://www.2carpros.com/articles/how-to-check-fuel-system-pressure-and-regulator

Hope this all helps and thanks for using 2CarPros.