While driving down the road and my wheel is.

I would be checking the wheel bearing first, not uncommon for bearings to be noisy when loaded up one way and quiet the other.

Yup, I'd check the wheel bearing too. Jack it up on the side it makes noise and get the wheel off the ground. Grab the tire at 9 and 3 o'clock and try to turn it. You'll feel if the bearing is loose. Do this for the front and rear tires, sometimes noises resonate to different ends of the car making it a bit confusing to tell where they're coming from.

Bearings are $20-40 a set, just do both, assuming that's what's wrong with it. I couldn't see them getting more than an hour for each side, so about $150 in labor bepending on where you take it. But do the bearing test so you know going in there what's wrong with it. Still could be other things.