Misfire rough idle and codes for knock sensor misfire and O2 sensor

I am getting a code for o2 sensor and misfire code. It idles really rough and loud a slight knock from around the driver side somewhere. I have fixed a lot of things including spark plugs, wires, EGR sensor, ignition coils, oil change. When I do drive it has a bad kick and hard time shifting tough start up and rough idle. I thought maybe it had a vacuum leak. I have sprayed throttle body cleaner all over, but I cannot hear any idle change. I have even tested my fuel injector connection with a voltmeter and they read just fine all the same. Can anybody help me because I am stumped and cannot keep putting money into it? But, my wife and I need the vehicle to get to work.