2006 Vauxhall Vectra noise when in gear

Had a slight noise coming from my car whilst driving yesterday it was making a slight humming sound whilst accelorating in gear. This morning iv gone to move the car and it was very juddery and I struggled to get out of reverse gear. Once I started going forward it shuddered to start with then drove fine but has now got a very loud whirling/screeching sound when accelorating. The car starts fine and makes no noise when out of gear and accelerate. I would like some advice before driving to garage incase I could be causing more damage by driving it. Thanks