I am replacing my stock air box with cone filter.

I am replacing my stock air box with cone filter and custom heat shield.

From the stock air box comes a hose that goes down and attaches to the bottom of the intake manifold.
This is a second hose, different from the one that has the mass air flow sensor.

Can I block off the hole at the bottom of the intake manifold or should I re-plumb to a different location?