If you are loosing coolant, there is a leak somewhere depletng it or it could be a bad head gasket or blown engine. Check the engine oil for presence of coolant. Ensure cooling fans are working. When a fault occurs, taking off the thermostat is not going to work, it might delay the time to overheat but it will still overheat eventually.
Monday, November 5th, 2012 AT 8:27 PM