2003 Lexus RX 300

Interior problem
2003 Lexus RX 300 6 cyl All Wheel Drive Automatic 72,000 miles

My remote is no longer working. At first I thought maybe it was the battery and still may be but I wanted to ask. When I hit lock, it will lock all doors but the passenger door. The horn signal no longer beeps when the vehicle is locked. It sounds like it locks but then it immediately unlocks. Any idea what my problem may be?
August 24, 2009.

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