2000 Ford Taurus

Engine Performance problem
2000 Ford Taurus 6 cyl Front Wheel Drive Automatic 190000 miles

I have a 2000 Ford Taurus wagon with 190000 miles. Recently it began to run rough and the code was a Cylunder 5 misfire. I replaced all the plugs and wires. I even took of the valve cover to see if any valves were sticking. Could it be the coil packl or is it something else? Thanks!
September 1, 2008.

Did you test for spark at the #5 wire?
Start with the basics, and work your way up, Last tune up was? Wires plugs ALL filters? If all that is ok, check for a stuck EGR, then test fuel pump pressure, If it won't restart, determine what's missing, the engine needs three things to run, Spark at all plugs, gas to all cylinders, and compression in all cylinders, tho an engine may run lacking one in one cylinder, it won't run very well!
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Sep 1, 2008.