No engines are interchangeable these days. You car has an operating system for one specific engine and nothing else. It's also against Federal law to modify a Federally emission certified vehicle in any way.

Answered by Wrenchtech (expert)
14,713 answers provided

Thanks for reply. So it is possible to replace my rx300 engine short block by any other 1mzfe short block (like camry, sienna,avalon and highlander)

Response from nergui
2 questions asked

That is a question to put to a salvage yard as they have access to interchange books that the rest of us don't have. They can tell you if the block is exactly the same or not.

Answered by Wrenchtech (expert)
14,713 answers provided

Thanks for the reply I'll ask them.

Response from nergui
2 questions asked